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Human CSF1R ELISA Kit

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  • Alternative name

    Human CSF-1 receptor ELISA Kit;Human CSF-1-R ELISA Kit;Human CSF-1R ELISA Kit;Human M-CSF-R ELISA Kit;Human proto-oncogene c-Fms ELISA Kit;Human FMS ELISA Kit;Human C-FMS ELISA Kit;Human CD115 ELISA Kit;Human CSFR ELISA Kit;Human FIM2 ELISA Kit;Human HDLS ELISA Kit;Human colony stimulating factor 1 receptor ELISA Kit;Human macrophage colony-stimulating factor 1 receptor ELISA Kit;Human CD115 antigen ELISA Kit;Human FMS proto-oncogene ELISA Kit;Human McDonough feline sarcoma viral (v-fms) oncogene homolog ELISA Kit;Human macrophage colony stimulating factor I receptor ELISA Kit;
  • Catalog
    E010307
  • species
    Human
  • GeneCSF1R
  • SpecificityNatural and recombinant human CSF1R
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity< 10pg/ml
  • Intended UseHuman CSF1R ELISA Kit allows for the in vitro quantitative determination of CSF1R , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical    Principle of the assay: human CSF1R ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from mouse specific for CSF1R has been precoated onto 96-well plates. Standards(NSO, I20-E512) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for CSF1R is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the human CSF1R amount of sample captured in plate. Background: CSF1R(Colony stimulating factor 1 receptor),also known as M-CSFR and CD115, is a cell-surface protein encoded, in humans, by the CSF1R gene. The gene is located on long arm of chromosome 5 (5q32) on the Crick (minus) strand. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. The encoded protein is a single pass type I membrane protein and acts as the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. Both CSF1R, and its ligand colony stimulating factor 1 play an important role in the development of the mammary gland and may be involved in the process of mammary gland carcinogenesis.
  • Human Macrophage colony-stimulating factor 1 receptor Protein information
  • Uniprot ID CSF1R_HUMAN
  • Uniprot AC P07333; B5A955; D3DQG2; Q6LDW5; Q6LDY4; Q86VW7;
  • UniGene Hs.586219;
  • GeneID 1436
  • KEGG hsa:1436;
  • Human Macrophage colony-stimulating factor 1 receptor Protein SEQUENCE

  • SEQUENCE 972 AA; 107984 MW; A8D99BE237573FE8 CRC64;

    MGPGVLLLLL VATAWHGQGI PVIEPSVPEL VVKPGATVTL RCVGNGSVEW

    DGPPSPHWTL YSDGSSSILS TNNATFQNTG TYRCTEPGDP LGGSAAIHLY

    VKDPARPWNV LAQEVVVFED QDALLPCLLT DPVLEAGVSL VRVRGRPLMR

    HTNYSFSPWH GFTIHRAKFI QSQDYQCSAL MGGRKVMSIS IRLKVQKVIP

    GPPALTLVPA ELVRIRGEAA QIVCSASSVD VNFDVFLQHN NTKLAIPQQS

    DFHNNRYQKV LTLNLDQVDF QHAGNYSCVA SNVQGKHSTS MFFRVVESAY

    LNLSSEQNLI QEVTVGEGLN LKVMVEAYPG LQGFNWTYLG PFSDHQPEPK

    LANATTKDTY RHTFTLSLPR LKPSEAGRYS FLARNPGGWR ALTFELTLRY

    PPEVSVIWTF INGSGTLLCA ASGYPQPNVT WLQCSGHTDR CDEAQVLQVW

    DDPYPEVLSQ EPFHKVTVQS LLTVETLEHN QTYECRAHNS VGSGSWAFIP

    ISAGAHTHPP DEFLFTPVVV ACMSIMALLL LLLLLLLYKY KQKPKYQVRW

    KIIESYEGNS YTFIDPTQLP YNEKWEFPRN NLQFGKTLGA GAFGKVVEAT

    AFGLGKEDAV LKVAVKMLKS TAHADEKEAL MSELKIMSHL GQHENIVNLL

    GACTHGGPVL VITEYCCYGD LLNFLRRKAE AMLGPSLSPG QDPEGGVDYK

    NIHLEKKYVR RDSGFSSQGV DTYVEMRPVS TSSNDSFSEQ DLDKEDGRPL

    ELRDLLHFSS QVAQGMAFLA SKNCIHRDVA ARNVLLTNGH VAKIGDFGLA

    RDIMNDSNYI VKGNARLPVK WMAPESIFDC VYTVQSDVWS YGILLWEIFS

    LGLNPYPGIL VNSKFYKLVK DGYQMAQPAF APKNIYSIMQ ACWALEPTHR

    PTFQQICSFL QEQAQEDRRE RDYTNLPSSS RSGGSGSSSS ELEEESSSEH

    LTCCEQGDIA QPLLQPNNYQ FC

  • UCSC uc003lrm.3; human. [P07333-1];



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