Human IL1R2 ELISA Kit

Alternative name
Human IL-1R-2 ELISA Kit;Human IL-1RT-2 ELISA Kit;Human IL-1RT2 ELISA Kit;Human CD121 antigen-like family member B ELISA Kit;Human CDw121b ELISA Kit;Human IL-1 type II receptor ELISA Kit;Human interleukin-1 receptor beta ELISA Kit;Human IL-1R-beta ELISA Kit;Human interleukin-1 receptor type II ELISA Kit;Human mIL-1R2 ELISA Kit;Human mIL-1RII ELISA Kit;Human sIL-1R2 ELISA Kit;Human sIL-1RII ELISA Kit;Human IL1RB ELISA Kit;Human CD121b ELISA Kit;Human IL1R2c ELISA Kit;Human interleukin 1 receptor type 2 ELISA Kit;Human interleukin-1 receptor type 2 ELISA Kit;Human antigen CDw121b ELISA Kit;Human interleukin 1 receptor type II variant 3 ELISA Kit;Human type II interleukin-1 receptor, beta ELISA Kit;
Catalog
E019411
species
Human
GeneIL1R2
SpecificityThe Human IL-1R2 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human IL-1R2 proteins within the range of 31.2 pg/ml - 2000 pg/ml.
SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
Sensitivity10 pg/ml.
Intended UseHuman IL1R2 ELISA Kit allows for the in vitro quantitative determination of IL1R2 , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
StorageStore the whole ELISA kit at 4℃
Product Description
specificalPrinciple of the Assay||The Human IL-1R2 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Human IL-1R2 in Cell Culture Supernatants, Serum. This assay employs an antibody specific for Human IL-1R2 coated on a 96-well plate. Standards and samples are pipetted into the wells and IL-1R2 present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Human IL-1R2 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of IL-1R2 bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm. Background/Introduction: Interleukin 1 receptor, type II (IL1R2) also known as CD121b (Cluster of Differentiation 121b) is an interleukin receptor. The protein encoded by this gene is a cytokine receptor that belongs to the interleukin-1 receptor family. It is mapped to 2q11.2. IL1R2 binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I (IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. IL1R2 also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. The secreted IL1R2 recruits secreted IL1RAP with high affinity, and this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
Human Interleukin-1 receptor type 2, soluble form Protein information
Uniprot ID IL1R2_HUMAN
Uniprot AC P27930; D3DVJ5; Q6LCE6; Q9UE68;
UniGene Hs.25333;
GeneID 7850
KEGG hsa:7850;
Human Interleukin-1 receptor type 2, soluble form Protein SEQUENCE
SEQUENCE 398 AA; 45421 MW; 2C2A03ADA6F3AC5B CRC64;
MLRLYVLVMG VSAFTLQPAA HTGAARSCRF RGRHYKREFR LEGEPVALRC
PQVPYWLWAS VSPRINLTWH KNDSARTVPG EEETRMWAQD GALWLLPALQ
EDSGTYVCTT RNASYCDKMS IELRVFENTD AFLPFISYPQ ILTLSTSGVL
VCPDLSEFTR DKTDVKIQWY KDSLLLDKDN EKFLSVRGTT HLLVHDVALE
DAGYYRCVLT FAHEGQQYNI TRSIELRIKK KKEETIPVII SPLKTISASL
GSRLTIPCKV FLGTGTPLTT MLWWTANDTH IESAYPGGRV TEGPRQEYSE
NNENYIEVPL IFDPVTREDL HMDFKCVVHN TLSFQTLRTT VKEASSTFSW
GIVLAPLSLA FLVLGGIWMH RRCKHRTGKA DGLTVLWPHH QDFQSYPK
UCSC uc002tbm.4; human. [P27930-1];

Category

Human IL1R2 ELISA Kit