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Human IFNL1 ELISA Kit

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  • Alternative name

    Human IFN-lambda-1 ELISA Kit;Human cytokine Zcyto21 ELISA Kit;Human interleukin-29 ELISA Kit;Human IL-29 ELISA Kit;Human IL29 ELISA Kit;Human ZCYTO21 ELISA Kit;Human interferon lambda 1 ELISA Kit;Human interferon lambda-1 ELISA Kit;Human interleukin 29 (interferon, lambda 1) ELISA Kit;
  • Catalog
    E019457
  • species
    Human
  • GeneIFNL1
  • SpecificityNatural and recombinant human IL-29
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity< 10pg/ml
  • Intended UseHuman IFNL1 ELISA Kit allows for the in vitro quantitative determination of IFNL1 , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical    Principle of the assay: human IL-29 ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from mouse specific for IL-29 has been precoated onto 96-well plates. Standards(NSO, G20-T200) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for IL-29 is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the human IL-29 amount of sample captured in plate. Background: Interferon lambda-1, also called Interleukin-29 (IL-29) is a protein that in humans is encoded by the IL29 gene. IL-29 is a member of the helical cytokine family and is a type III interferon. This gene is mapped to 19q13.2. It is a cytokine with immunomodulatory activity. This gene may play a role in antiviral immunity. It can up-regulates MHC class I antigen expression. It is the ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1. The ligand/receptor complex seems to signal through the Jak-STAT pathway. IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses.
  • Human Interferon lambda-1 Protein information
  • Uniprot ID IFNL1_HUMAN
  • Uniprot AC Q8IU54; A0AV25; Q17R34;
  • UniGene Hs.406745;
  • GeneID 282618
  • KEGG hsa:282618;
  • Human Interferon lambda-1 Protein SEQUENCE

  • SEQUENCE 200 AA; 21898 MW; D4433B9462DCB4A1 CRC64;

    MAAAWTVVLV TLVLGLAVAG PVPTSKPTTT GKGCHIGRFK SLSPQELASF

    KKARDALEES LKLKNWSCSS PVFPGNWDLR LLQVRERPVA LEAELALTLK

    VLEAAAGPAL EDVLDQPLHT LHHILSQLQA CIQPQPTAGP RPRGRLHHWL

    HRLQEAPKKE SAGCLEASVT FNLFRLLTRD LKYVADGNLC LRTSTHPEST

  • UCSC uc002okv.4; human.;



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