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Human HCN1 ELISA Kit

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  • Alternative name

    Human brain cyclic nucleotide-gated channel 1 ELISA Kit;Human BCNG-1 ELISA Kit;Human BCNG1 ELISA Kit;Human EIEE24 ELISA Kit;Human HAC-2 ELISA Kit;Human hyperpolarization activated cyclic nucleotide gated potassium channel 1 ELISA Kit;Human potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 ELISA Kit;
  • Catalog
    E030327
  • species
    Human
  • GeneHCN1
  • SpecificityThis assay has high sensitivity and excellent specificity for detection of Human HCN1. No significant cross-reactivity or interference between Human HCN1 and analogues was observed.
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity26 pg/mL (mean of 6 independent assays).
  • Intended UseHuman HCN1 ELISA Kit allows for the in vitro quantitative determination of HCN1 , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical    Intended Uses: For the quantitative detection of Potassium/sodium hyperpolarizationactivated cyclic nucleotide-gated channel 1 (HCN1) concentration in serum, plasma and other biological fluids. Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitative HCN1 in Human serum, plasma. An antibody specific for HCN1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any HCN1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin - conjugated antibody specific for HCN1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of HCN1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
  • Human Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 Protein information
  • Uniprot ID HCN1_HUMAN
  • Uniprot AC O60741;
  • UniGene Hs.353176;
  • GeneID 348980
  • KEGG hsa:348980;
  • Human Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 Protein SEQUENCE

  • SEQUENCE 890 AA; 98796 MW; A62F5E79C01257A2 CRC64;

    MEGGGKPNSS SNSRDDGNSV FPAKASATGA GPAAAEKRLG TPPGGGGAGA

    KEHGNSVCFK VDGGGGGGGG GGGGEEPAGG FEDAEGPRRQ YGFMQRQFTS

    MLQPGVNKFS LRMFGSQKAV EKEQERVKTA GFWIIHPYSD FRFYWDLIML

    IMMVGNLVII PVGITFFTEQ TTTPWIIFNV ASDTVFLLDL IMNFRTGTVN

    EDSSEIILDP KVIKMNYLKS WFVVDFISSI PVDYIFLIVE KGMDSEVYKT

    ARALRIVRFT KILSLLRLLR LSRLIRYIHQ WEEIFHMTYD LASAVVRIFN

    LIGMMLLLCH WDGCLQFLVP LLQDFPPDCW VSLNEMVNDS WGKQYSYALF

    KAMSHMLCIG YGAQAPVSMS DLWITMLSMI VGATCYAMFV GHATALIQSL

    DSSRRQYQEK YKQVEQYMSF HKLPADMRQK IHDYYEHRYQ GKIFDEENIL

    NELNDPLREE IVNFNCRKLV ATMPLFANAD PNFVTAMLSK LRFEVFQPGD

    YIIREGAVGK KMYFIQHGVA GVITKSSKEM KLTDGSYFGE ICLLTKGRRT

    ASVRADTYCR LYSLSVDNFN EVLEEYPMMR RAFETVAIDR LDRIGKKNSI

    LLQKFQKDLN TGVFNNQENE ILKQIVKHDR EMVQAIAPIN YPQMTTLNST

    SSTTTPTSRM RTQSPPVYTA TSLSHSNLHS PSPSTQTPQP SAILSPCSYT

    TAVCSPPVQS PLAARTFHYA SPTASQLSLM QQQPQQQVQQ SQPPQTQPQQ

    PSPQPQTPGS STPKNEVHKS TQALHNTNLT REVRPLSASQ PSLPHEVSTL

    ISRPHPTVGE SLASIPQPVT AVPGTGLQAG GRSTVPQRVT LFRQMSSGAI

    PPNRGVPPAP PPPAAALPRE SSSVLNTDPD AEKPRFASNL

  • UCSC uc003jok.4; human.;



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