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Human SYNJ2 ELISA Kit

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  • Alternative name

    Human synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2 ELISA Kit;Human KIAA0348 ELISA Kit;Human INPP5H ELISA Kit;Human synaptojanin 2 ELISA Kit;Human synaptojanin-2 ELISA Kit;Human inositol phosphate 5'-phosphatase 2 ELISA Kit;Human inositol polyphosphate-5-phosphatase H ELISA Kit;Human phosphoinositide 5-phosphatase ELISA Kit;
  • Catalog
    E037089
  • species
    Human
  • GeneSYNJ2
  • SpecificityThis assay has high sensitivity and excellent specificity for detection of Human SYNJ2. No significant cross-reactivity or interference between Human SYNJ2 and analogues was observed.
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity40 pg/ml
  • Intended UseHuman SYNJ2 ELISA Kit allows for the in vitro quantitative determination of SYNJ2 , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical    Introduction: Synaptojanin 2 (SYNJ2) is a ubiquitously expressed inositol 5 phosphatase, which may be involved in distinct membrane trafficking and signal transduction pathways. Synaptojanin 2 is a Rac1 effector and may mediate the inhibitory effect of Rac1 on clathrin mediated endocytosis. Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to SYNJ2. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for SYNJ2 and Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB (3,3',5,5' tetramethyl-benzidine) substrate solution is added to each well. Only those wells that contain SYNJ2, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of SYNJ2 in the samples is then determined by comparing the O.D. of the samples to the standard curve.
  • Human Synaptojanin-2 Protein information
  • Uniprot ID SYNJ2_HUMAN
  • Uniprot AC O15056; Q5TA13; Q5TA16; Q5TA19; Q86XK0; Q8IZA8; Q9H226;
  • UniGene Hs.434494;
  • GeneID 8871
  • KEGG hsa:8871;
  • Human Synaptojanin-2 Protein SEQUENCE

  • SEQUENCE 1496 AA; 165538 MW; 7CC9E368585ACF21 CRC64;

    MALSKGLRLL GRLGAEGDCS VLLEARGRDD CLLFEAGTVA TLAPEEKEVI

    KGQYGKLTDA YGCLGELRLK SGGTSLSFLV LVTGCTSVGR IPDAEIYKIT

    ATDFYPLQEE AKEEERLIAL KKILSSGVFY FSWPNDGSRF DLTVRTQKQG

    DDSSEWGNSF FWNQLLHVPL RQHQVSCCDW LLKIICGVVT IRTVYASHKQ

    AKACLVSRVS CERTGTRFHT RGVNDDGHVS NFVETEQMIY MDDGVSSFVQ

    IRGSVPLFWE QPGLQVGSHH LRLHRGLEAN APAFDRHMVL LKEQYGQQVV

    VNLLGSRGGE EVLNRAFKKL LWASCHAGDT PMINFDFHQF AKGGKLEKLE

    TLLRPQLKLH WEDFDVFTKG ENVSPRFQKG TLRMNCLDCL DRTNTVQSFI

    ALEVLHLQLK TLGLSSKPIV DRFVESFKAM WSLNGHSLSK VFTGSRALEG

    KAKVGKLKDG ARSMSRTIQS NFFDGVKQEA IKLLLVGDVY GEEVADKGGM

    LLDSTALLVT PRILKAMTER QSEFTNFKRI RIAMGTWNVN GGKQFRSNVL

    RTAELTDWLL DSPQLSGATD SQDDSSPADI FAVGFEEMVE LSAGNIVNAS

    TTNKKMWGEQ LQKAISRSHR YILLTSAQLV GVCLYIFVRP YHVPFIRDVA

    IDTVKTGMGG KAGNKGAVGI RFQFHSTSFC FICSHLTAGQ SQVKERNEDY

    KEITQKLCFP MGRNVFSHDY VFWCGDFNYR IDLTYEEVFY FVKRQDWKKL

    LEFDQLQLQK SSGKIFKDFH EGAINFGPTY KYDVGSAAYD TSDKCRTPAW

    TDRVLWWRKK HPFDKTAGEL NLLDSDLDVD TKVRHTWSPG ALQYYGRAEL

    QASDHRPVLA IVEVEVQEVD VGARERVFQE VSSFQGPLDA TVVVNLQSPT

    LEEKNEFPED LRTELMQTLG SYGTIVLVRI NQGQMLVTFA DSHSALSVLD

    VDGMKVKGRA VKIRPKTKDW LKGLREEIIR KRDSMAPVSP TANSCLLEEN

    FDFTSLDYES EGDILEDDED YLVDEFNQPG VSDSELGGDD LSDVPGPTAL

    APPSKSPALT KKKQHPTYKD DADLVELKRE LEAVGEFRHR SPSRSLSVPN

    RPRPPQPPQR PPPPTGLMVK KSASDASISS GTHGQYSILQ TARLLPGAPQ

    QPPKARTGIS KPYNVKQIKT TNAQEAEAAI RCLLEARGGA SEEALSAVAP

    RDLEASSEPE PTPGAAKPET PQAPPLLPRR PPPRVPAIKK PTLRRTGKPL

    SPEEQFEQQT VHFTIGPPET SVEAPPVVTA PRVPPVPKPR TFQPGKAAER

    PSHRKPASDE APPGAGASVP PPLEAPPLVP KVPPRRKKSA PAAFHLQVLQ

    SNSQLLQGLT YNSSDSPSGH PPAAGTVFPQ GDFLSTSSAT SPDSDGTKAM

    KPEAAPLLGD YQDPFWNLLH HPKLLNNTWL SKSSDPLDSG TRSPKRDPID

    PVSAGASAAK AELPPDHEHK TLGHWVTISD QEKRTALQVF DPLAKT

  • UCSC uc003qqx.3; human. [O15056-1];



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