Mouse Cd6 ELISA Kit

Alternative name
Mouse CD6 antigen ELISA Kit;Mouse T-cell differentiation antigen CD6 ELISA Kit;
Catalog
E047750
species
Mouse
GeneCd6
SpecificityNatural and recombinant mouse CD6
SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
Sensitivity< 10pg/ml
Intended UseMouse Cd6 ELISA Kit allows for the in vitro quantitative determination of Cd6 , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
StorageStore the whole ELISA kit at 4℃
Product Description
specificalPrinciple of the assay: mouse CD6 ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from rat specific for CD6 has been precoated onto 96-well plates. Standards(NSO, L18-G396) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for CD6 is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the mouse CD6 amount of sample captured in plate. Background: CD6(Cluster of Differentiation 6) is a human protein encoded by the CD6 gene. It is mapped to 11q12.2. CD6 is expressed predominantly in peripheral T cells and mature medullary thymocytes. This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. What's more, this gene may be associated with susceptibility to multiple sclerosis.
Mouse T-cell differentiation antigen CD6 Protein information
Uniprot ID CD6_MOUSE
Uniprot AC Q61003; Q60679; Q61004; Q8BGK1;
UniGene Mm.290897;
GeneID 12511
KEGG mmu:12511;
Mouse T-cell differentiation antigen CD6 Protein SEQUENCE
SEQUENCE 665 AA; 72255 MW; 8FF16DB37494D54F CRC64;
MWLFLGIAGL LTAVLSGLPS PAPSGQHKNG TIPNMTLDLE ERLGIRLVNG
SSRCSGSVKV LLESWEPVCA AHWNRAATEA VCKALNCGDS GKVTYLMPPT
SELPPGATSG NTSSAGNTTW ARAPTERCRG ANWQFCKVQD QECSSDRRLV
WVTCAENQAV RLVDGSSRCA GRVEMLEHGE WGTVCDDTWD LQDAHVVCKQ
LKCGWAVKAL AGLHFTPGQG PIHRDQVNCS GTEAYLWDCP GRPGDQYCGH
KEDAGVVCSE HQSWRLTGGI DSCEGQVEVY FRGVWSTVCD SEWYPSEAKV
LCRSLGCGSA VARPRGLPHS LDGRMYYSCK GQEPALSTCS WRFNNSNLCS
QSRAARVVCS GSQRHLNLST SEVPSRVPVT IESSVPVSVK DKDSQGLTLL
ILCIVLGILL LVSTIFIVIL LLRAKGQYAL PASVNHQQLS TANQAGINNY
HPVPITIAKE APMLFIQPRV PADSDSSSDS DYEHYDFSSQ PPVALTTFYN
SQRHRVTEEE AQQNRFQMPP LEEGLEELHV SHIPAADPRP CVADVPSRGS
QYHVRNNSDS STSSEEGYCN DPSSKPPPWN SQAFYSEKSP LTEQPPNLEL
AGSPAVFSGP SADDSSSTSS GEWYQNFQPP PQHPPAEQFE CPGPPGPQTD
SIDDDEEDYD DIGAA
UCSC uc008gqz.1; mouse. [Q61003-3];

Category

Mouse Cd6 ELISA Kit

Mouse CD6 antigen ELISA Kit;Mouse T-cell differentiation antigen CD6 ELISA Kit;