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Mouse Il17c ELISA Kit

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  • Alternative name

    Mouse IL-17C ELISA Kit;Mouse cytokine CX2 ELISA Kit;Mouse interleukin 17C ELISA Kit;Mouse interleukin-17C ELISA Kit;
  • Catalog
    E056306
  • species
    Mouse
  • GeneIl17c
  • SpecificityThe Mouse IL-17C ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Mouse IL-17C proteins within the range of 125 pg/ml - 8000 pg/ml.
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity10 pg/ml.
  • Intended UseMouse Il17c ELISA Kit allows for the in vitro quantitative determination of Il17c , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical    Principle of the Assay||The Mouse IL-17C ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Mouse IL-17C in Cell Culture Supernatants, Serum, Plasma. This assay employs an antibody specific for Mouse IL-17C coated on a 96-well plate. Standards and samples are pipetted into the wells and IL-17C present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Mouse IL-17C antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of IL-17C bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm. Background/Introduction: IL17C, also known as CX2, is a protein that in humans is encoded by the IL17C gene. IL17C is mapped to 16q24.3. The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells. IL17C is an essential autocrine cytokine regulating innate epithelial immune responses. It also plays an important role in the pathogenesis of inflammatory arthritis.
  • Mouse Interleukin-17C Protein information
  • Uniprot ID IL17C_MOUSE
  • Uniprot AC Q8K4C5; A6H6F0;
  • UniGene Mm.222808;
  • GeneID 234836
  • KEGG mmu:234836;
  • Mouse Interleukin-17C Protein SEQUENCE

  • SEQUENCE 194 AA; 21592 MW; 95797A630574BD1E CRC64;

    MSLLLLGWLP TGMTHQDPPS WGKPRSHRTL RCYSAEELSH GQAPPHLLTR

    SARWEQALPV ALVASLEATG HRRQHEGPLA GTQCPVLRPE EVLEADTHER

    SISPWRYRID TDENRYPQKL AVAECLCRGC INAKTGRETA ALNSVQLLQS

    LLVLRRQPCS RDGTADPTPG SFAFHTEFIR VPVGCTCVLP RSTQ

  • UCSC uc012gmc.1; mouse.;



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