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Human CD93 ELISA Kit

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  • Alternative name

    Human C1q/MBL/SPA receptor ELISA Kit;Human C1qR ELISA Kit;Human C1qR(P) ELISA Kit;Human C1qRP ELISA Kit;Human CDw93 ELISA Kit;Human complement component 1 q subcomponent receptor 1 ELISA Kit;Human matrix-remodeling-associated protein 4 ELISA Kit;Human C1QR1 ELISA Kit;Human MXRA4 ELISA Kit;Human ECSM3 ELISA Kit;Human dJ737E23.1 ELISA Kit;Human CD93 molecule ELISA Kit;Human complement component C1q receptor ELISA Kit;Human C1q receptor 1 ELISA Kit;Human CD93 antigen ELISA Kit;Human matrix-remodelling associated 4 ELISA Kit;
  • Catalog
    E007545
  • species
    Human
  • GeneCD93
  • SpecificityThe Human CD93 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human CD93 proteins within the range of 78 pg/ml - 5000 pg/ml.
  • SamplesSerum, Plasma , tissue homogenates,Cell culture supernates,Other biological fluids.
  • Sensitivity10 pg/ml.
  • Intended UseHuman CD93 ELISA Kit allows for the in vitro quantitative determination of CD93 , concentrations in serum, Plasma , tissue homogenates and Cell culture supernates and Other biological fluids.
  • StorageStore the whole ELISA kit at 4℃
  • Product Description
    specifical    Principle of the Assay||The Human CD93 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Human CD93 in Cell Culture Supernatants, Serum, Plasma. This assay employs an antibody specific for Human CD93 coated on a 96-well plate. Standards and samples are pipetted into the wells and CD93 present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Human CD93 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of CD93 bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm. Background/Introduction: CD93 (Cluster of Differentiation 93) is a protein that in humans is encoded by the CD93 gene. CD93 belongs to the Group XIV C-Type lectin family and is mapped to 20p11.21. The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton. It has also showed that this receptor is a positive marker for all bone marrow-repopulating stem cells because it is expressed on both CD34-negative and CD34-positive stem cells from umbilical cord blood and adult bone marrow. In addition, highly purified lineage-negative cells with the CD93 protein not only have bone marrow-repopulating capacity but also can differentiate into human hepatocytes in vivo.
  • Human Complement component C1q receptor Protein information
  • Uniprot ID C1QR1_HUMAN
  • Uniprot AC Q9NPY3; O00274;
  • UniGene Hs.97199;
  • GeneID 22918
  • KEGG hsa:22918;
  • Human Complement component C1q receptor Protein SEQUENCE

  • SEQUENCE 652 AA; 68560 MW; EECA0FEAC55FCAC2 CRC64;

    MATSMGLLLL LLLLLTQPGA GTGADTEAVV CVGTACYTAH SGKLSAAEAQ

    NHCNQNGGNL ATVKSKEEAQ HVQRVLAQLL RREAALTARM SKFWIGLQRE

    KGKCLDPSLP LKGFSWVGGG EDTPYSNWHK ELRNSCISKR CVSLLLDLSQ

    PLLPSRLPKW SEGPCGSPGS PGSNIEGFVC KFSFKGMCRP LALGGPGQVT

    YTTPFQTTSS SLEAVPFASA ANVACGEGDK DETQSHYFLC KEKAPDVFDW

    GSSGPLCVSP KYGCNFNNGG CHQDCFEGGD GSFLCGCRPG FRLLDDLVTC

    ASRNPCSSSP CRGGATCVLG PHGKNYTCRC PQGYQLDSSQ LDCVDVDECQ

    DSPCAQECVN TPGGFRCECW VGYEPGGPGE GACQDVDECA LGRSPCAQGC

    TNTDGSFHCS CEEGYVLAGE DGTQCQDVDE CVGPGGPLCD SLCFNTQGSF

    HCGCLPGWVL APNGVSCTMG PVSLGPPSGP PDEEDKGEKE GSTVPRAATA

    SPTRGPEGTP KATPTTSRPS LSSDAPITSA PLKMLAPSGS PGVWREPSIH

    HATAASGPQE PAGGDSSVAT QNNDGTDGQK LLLFYILGTV VAILLLLALA

    LGLLVYRKRR AKREEKKEKK PQNAADSYSW VPERAESRAM ENQYSPTPGT

    DC

  • UCSC uc002wsv.4; human.;



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