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Alternative name
LHR, MDU2, MDU3, MIC4 antibody
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Catalog
A001483
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityMonoclonal Antibody
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Host Mouse
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Species ReactivityHuman
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Applications Tested/SuitableELISA,WB,IHC,IF,FC
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PurificationProtein A+G purification
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ImmunogenCD44 molecule (Indian blood group)
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IHCImmunohistochemistry of paraffin-embedded human lung cancer slide using A001483( CD44 Antibody) at dilution of 1:50
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Western BlotHeLa cells were subjected to SDS PAGE followed by western blot with A001483(CD44 antibody) at dilution of 1:1000
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Recommended dilutionWB:1：500-1：5000;IHC:1：50-1：200;IF:1：10-1：100
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Product Description specificalReceptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Receptor for LGALS9; the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (By similarity).
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Gene nameCD44
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locationCell membrane?
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Uniprot IDP16070
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Calculated M.W.82kDa
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Observed M.W.80-95 kDa
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