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Alternative name
ALDOC, Aldolase C, Brain type aldolase, Fructose bisphosphate aldolase C antibody
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Catalog
A000304
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityMonoclonal Antibody
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Host Mouse
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Species ReactivityHuman
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Applications Tested/SuitableELISA,WB,IF
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PurificationProtein A+G purification
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Immunogenaldolase C, fructose-bisphosphate
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IHCImmunohistochemistry of paraffin-embedded human liver cancer tissue slide using A000304( ALDOC Antibody) at dilution of 1:200 . heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
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Western Blothuman heart tissue were subjected to SDS PAGE followed by western blot with A000304(ALDOC antibody) at dilution of 1:10000
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Recommended dilutionWB :1:5000-1:50000;IHC:1:50-1:500;IF:1:20-1:200
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Product Description specificalFructose-bisphosphate aldolase C (ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate and is strongly expressed in mammalian brain together with ALDOA and is alsopresent in the heart and spleen of some species(PMID:9363598). It is involed in glycolysis as an important enzyme. Phospholipase D2 and inositol 1,4,5-triphosphate interact with ALDOC in signal transduction. Meanwhile, the protein expression of ALDOC has been reported to be regulated in brain tumor, hepatomas, and lung cancer(PMID:21548097).
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Gene nameALDOC
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locationmitochondrion,ytosol,xtracellular exosome
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Uniprot IDP09972
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Calculated M.W.39kDa
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Observed M.W.40 kDa
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