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Alternative name
AMOT, angiomotin, KIAA1071 antibody
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Catalog
A000368
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityMonoclonal Antibody
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Host Mouse
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Species ReactivityHuman
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Applications Tested/SuitableELISA,WB,IHC
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PurificationProtein A+G purification
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Immunogenangiomotin
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IHCImmunohistochemistry of paraffin-embedded human placenta using A000368(AMOT antibody) at dilution of 1:100
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Western BlotGC-7901 cells were subjected to SDS PAGE followed by western blot with A000368( AMOT Antibody) at dilution of 1:2000
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Recommended dilutionWB :1:1000-1:10000;IHC:1:20-1:200
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Product Description specificalPlays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions.
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Gene nameAMOT
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locationCell junction,Tight junction
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Uniprot IDQ4VCS5
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Calculated M.W.118kDa
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Observed M.W.80 kDa; 130 kDa
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