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Alternative name
SGRF antibody
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Catalog
A004256
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityMonoclonal Antibody
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Host Mouse
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Species ReactivityHuman
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Applications Tested/SuitableELISA,WB,IHC
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PurificationProtein A+G purification
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Immunogeninterleukin 23, alpha subunit p19
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IHCImmunohistochemistry of paraffin-embedded human pancreas tissue slide using A004256( IL23A Antibody) at dilution of 1:50
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Western BlotUntransfeted HEK293 cells (left) and IL23A transfected HEK293 cells (right) were subjected to SDS-PAGE followed by western blot with A004256(IL23A monoclonal Antibody) at dilution of 1:1000
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalAssociates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak- Stat signaling cascade, stimulates memory rather than naive T- cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
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Gene nameIL23A
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Uniprot IDQ9NPF7
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Observed M.W.21 kDa
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