-
Alternative name
B cell stimulatory factor 2, BSF 2, BSF2, CDF, CTL differentiation factor, HGF, HSF, Hybridoma growth factor, IFN beta 2, IFNB2, IL 6, IL6, IL-6, Interferon beta 2, Interleukin 6 antibody
-
Catalog
A004283
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityMonoclonal Antibody
-
Host Mouse
-
Species ReactivityHuman
-
Applications Tested/SuitableELISA,IHC,WB
-
PurificationProtein A+G purification
-
Immunogeninterleukin 6 (interferon, beta 2)
-
IHCImmunohistochemistry of paraffin-embedded human cervical cancer tissue slide using A004283( IL6 Antibody) at dilution of 1:50
-
Western BlotJurkat cells were subjected to SDS PAGE followed by western blot with A004283(IL6 antibody) at dilution of 1:1000
-
Recommended dilutionWB:1:500-1:5000；IHC:1:20-1:200
-
Product Description specificalInterleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 Plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.
-
Gene nameIL6
-
Uniprot IDP05231
-
Calculated M.W.30kDa
-