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Alternative name
KRAS2, RASK2 antibody
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Catalog
A004642
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityMonoclonal Antibody
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Host Mouse
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Species ReactivityHuman
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Applications Tested/SuitableELISA,WB,IHC,FC
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PurificationProtein A+G purification
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Immunogenv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
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IHCImmunohistochemistry of paraffin-embedded human breast cancer tissue slide using A004642( KRAS Antibody) at dilution of 1:650 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
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Western BlotNeuro-2a cells were subjected to SDS PAGE followed by western blot with A004642( KRAS Antibody) at dilution of 1:10000
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalRas proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (PubMed:24623306).
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Gene nameKRAS
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Uniprot IDP01116
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Observed M.W.21 kDa
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