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Alternative name
MAGE3 antibody
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Catalog
A004937
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityMonoclonal Antibody
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Host Mouse
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Species ReactivityHuman
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Applications Tested/SuitableELISA,WB,IHC
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PurificationProtein A+G purification
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Immunogenmelanoma antigen family A, 3
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IHCImmunohistochemistry of paraffin-embedded human lung cancer tissue slide using A004937( MAGEA3 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
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Western Blotmouse brain tissue were subjected to SDS PAGE followed by western blot with A004937( MAGEA3 Antibody) at dilution of 1:2000
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Recommended dilutionWB : 1:1000-1:10000
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Product Description specificalProposed to enhance ubiquitin ligase activity of RING- type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
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Gene nameMAGEA3
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Uniprot IDP43357
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Observed M.W.35-55 kDa
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