Product Categories
-
Alternative name
BCL2L4 antibody
-
Catalog
A000811
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityMonoclonal Antibody
-
Host Mouse
-
Species ReactivityHuman,Mouse
-
Applications Tested/SuitableELISA,WB
-
PurificationProtein A+G purification
-
ImmunogenBCL2-associated X protein
-
Recommended dilutionWB : 1:500-1:5000
-
Product Description specificalAccelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
-
Gene nameBAX
-
Uniprot IDQ07812
-
Observed M.W.21 kDa
-