-
Alternative name
AW986256, B cell leukemia/lymphoma 2, Bcl2, C430015F12Rik, D630044D05Rik, D830018M01Rik antibody
-
Catalog
A000840
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityMonoclonal Antibody
-
Host Mouse
-
Species ReactivityHuman
-
Applications Tested/SuitableELISA,WB,FC,IP,IHC
-
PurificationProtein A+G purification
-
ImmunogenB-cell CLL/lymphoma 2
-
IHCImmunohistochemistry of paraffin-embedded human tonsillitis tissue slide using A000840( BCL2 Antibody) at dilution of 1:100
-
Western BlotJurkat cells were subjected to SDS PAGE followed by western blot with A000840( BCL2 Antibody) at dilution of 1:4000
-
Recommended dilutionWB : 1:200-1:2000
-
Product Description specificalSuppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785).
-
Gene nameBcl2
-
Uniprot IDP10415
-
Observed M.W.26 kDa
-