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Alternative name
Deubiquitinating enzyme 1, hUBP, ubiquitin specific peptidase 1, Ubiquitin thiolesterase 1, UBP, USP1 antibody
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Catalog
A009303
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityMonoclonal Antibody
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Host Mouse
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Species ReactivityHuman
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Applications Tested/SuitableELISA,WB,IHC
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PurificationProtein A+G purification
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Immunogenubiquitin specific peptidase 1
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IHCImmunohistochemistry of paraffin-embedded human cervical cancer using A009303(USP1 antibody) at dilution of 1:50
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Western BlotHepG2 cells were subjected to SDS PAGE followed by western blot with A009303( USP1 Antibody) at dilution of 1:2000
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Recommended dilutionWB : 1:1000-1:10000;IHC:1:20-1:200
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Product Description specificalNegative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2 (PubMed:15694335). Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA (PubMed:16531995). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity (PubMed:18082604, PubMed:26388029).
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Gene nameUSP1
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locationNucleus
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Uniprot IDO94782
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Calculated M.W.90kDa
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Observed M.W.110kd, 100kd
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