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Alternative name
VIL, VIL1, Villin, villin 1 antibody
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Catalog
A009407
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityMonoclonal Antibody
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Host Mouse
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB,IHC,IF,IP
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PurificationProtein A+G purification
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Immunogenvillin 1
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IHCImmunohistochemistry of paraffin-embedded human colon cancer tissue slide using A009407( VIL1 Antibody) at dilution of 1:50?
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Western Blothuman kidney tissue were subjected to SDS PAGE followed by western blot with A009407(VIL1 antibody) at dilution of 1:1000
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Recommended dilutionWB :1:500-1:5000;IHC:1:50-1:2000;IF:1:10-1:100;IP:1:500-1:5000
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Product Description specificalVillin 1 (VIL1) is a 95-kd F-actin bundling and severing protein and its expression is restricted to epithelial cells with a brush border, like epithelial cells of the intestinal mucosa, gall bladder, renal proximal tubules and ductuli efferentes of the testis. VIL1 has been reported to be an epithelial cell-specific anti-apoptotic protein, and to have an important function in regulating actin dynamics, cell morphology, epithelial-to-mesenchymal transitions, cell migration and cell survival. In addition, VIL1 is a useful diagnostic marker for of various cancer, like cervical and endometrial adenocarcinomas, renal cell carcinoma. VIL1 was recently identified as a novel biomarker predictive for postoperative recurrence and poorer prognosis of high serum AFP associated HCC.
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Gene nameVIL1
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locationCell projection,Cytoplasm,Cytoskeleton
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Uniprot IDP09327
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Calculated M.W.93kDa
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Observed M.W.93 kDa
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