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Alternative name
Activin receptor like kinase 1, ACVRL1, ACVRLK1, ALK 1, ALK1, HHT, HHT2, ORW2, SKR3, TSR I antibody
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Catalog
A000131
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman
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Applications Tested/SuitableELISA,WB,IHC,FC,IP
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PurificationImmunogen affinity purified
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Immunogenactivin A receptor type II-like 1
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IHCImmunohistochemistry of paraffin-embedded human heart tissue slide using A000131( ACVRL1 Antibody) at dilution of 1:200
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Western BlotJurkat cells were subjected to SDS PAGE followed by western blot with A000131(ACVRL1 antibody) at dilution of 1:400
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Recommended dilutionWB :1:200-1:1000;IHC:1:100-1:400;IP:1:200-1:1000
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Product Description specificalType I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
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Gene nameACVRL1
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locationCell membrane
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Uniprot IDP37023
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Calculated M.W.56kDa
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Observed M.W.63 kDa
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