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Alternative name
CDC42, CDC42Hs, G25K, G25K GTP binding protein antibody
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Catalog
A001530
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogencell division cycle 42 (GTP binding protein, 25kDa)
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IHCImmunohistochemistry of paraffin-embedded human pancreas cancer using A001530(CDC42 antibody) at dilution of 1:50
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Western Blotmouse brain tissue were subjected to SDS PAGE followed by western blot with A001530(CDC42 antibody) at dilution of 1:400
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Recommended dilutionWB : 1:200-1:1000
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Product Description specificalPlasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. Mediates CDC42-dependent cell migration.
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Gene nameCDC42
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Uniprot IDP60953
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Observed M.W.21 kDa
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