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Alternative name
3D3, 3D3/LYRIC, AEG 1, AEG1, LYRIC, LYRIC/3D3, metadherin, Metastasis adhesion protein, MTDH, Protein LYRIC antibody
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Catalog
A000189
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IF,IP
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PurificationImmunogen affinity purified
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Immunogenmetadherin
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IHCImmunohistochemistry of paraffin-embedded human breast cancer using A000189(AEG-1 antibody) at dilution of 1:50
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Western BlotMCF7 cells were subjected to SDS PAGE followed by western blot with A000189(AEG-1 antibody) at dilution of 1:1000
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Recommended dilutionWB :1:500-1:5000;IHC:1:20-1:200;IF:1:20-1:200;IP:1:500-1:5000
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Product Description specificalMTDH, also known as AEG-1, is a single-pass transmembrane protein with its gene located at chromosome 8q22 , the abnormalities of which have been identified in several tumor types. MTDH is overexpressed in a number of malignancies, such as breast cancer, malignant glioma, and neuroblastoma , and its overexpression is associated with poor clinical outcome. MTDH plays an important role in the regulation of carcinogenesis and tumor progression. This antibody got two bands about 70 kDa and 80 kDa in western blotting, possibly due to posttranslational modification. This antibody is specific to AEG-1/MTDH.
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Gene nameMTDH
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locationwidely
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Uniprot IDQ86UE4
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Calculated M.W.64kDa
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Observed M.W.65-70 kDa
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