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Alternative name
AFAP, AFAP 110, AFAP1, FLJ56849 antibody
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Catalog
A000192
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IF
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PurificationImmunogen affinity purified
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Immunogenactin filament associated protein 1
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Western Blotrat brain tissue were subjected to SDS PAGE followed by western blot with A000192( AFAP1 Antibody) at dilution of 1:1000
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Recommended dilutionWB :1:500-1:5000;IF:1:10-1:100
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Product Description specificalCan cross-link actin filaments into both network and bundle structures (By similarity). May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.
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Gene nameAFAP1
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locationCytoplasm,Cytoskeleton
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Uniprot IDQ8N556
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Calculated M.W.81kDa,observed 110kDa
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Observed M.W.110 kDa
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