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Alternative name
CSPG4, HMW MAA, MCSP, MCSPG, MEL CSPG, MSK16, NG2 antibody
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Catalog
A002025
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogenchondroitin sulfate proteoglycan 4
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IHCImmunohistochemistry of paraffin-embedded human lung cancer tissue slide using A002025( CSPG4,NG2 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
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Western BlotA375 cells were subjected to SDS PAGE followed by western blot with A002025(CSPG4,NG2 antibody) at dilution of 1:300
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Recommended dilutionWB : 1:500-1:5000
IHC : 1:50-1:500
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Product Description specificalCSPG4, also named as HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16 and NG2, is a proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. CSPG4 may inhibit neurite outgrowth and growth cone collapse during axon regeneration. It is cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. CSPG4 may regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. It modulates the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin.
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Gene nameCSPG4
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Uniprot IDQ6UVK1
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Calculated M.W.245kDa
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Observed M.W.240-250 kDa
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