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Alternative name
67 kDa cytokeratin, CK 1, CK1, Cytokeratin 1, keratin 1, KRT1 antibody
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Catalog
A002211
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,IP,IF,WB,IHC
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PurificationImmunogen affinity purified
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Immunogenkeratin 1
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IHCImmunohistochemistry of paraffin-embedded human lung cancer using A002211(KRT1-specific antibody) at dilution of 1:50
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Western Blotmouse skin tissue were subjected to SDS PAGE followed by western blot with A002211( KRT1-specific Antibody) at dilution of 1:1000
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Recommended dilutionWB:1:500-1:5000;IP:1:200-1:2000;IHC:1:20-1:200;IF:1:20-1:200
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Product Description specificalKeratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. Keratin-1 is type II keratin. It is a specific marker for terminal differentiation in mammalian epidermis. It is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. This antibody is specifically against ketatin I.
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Gene nameKRT1
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Uniprot IDP04264
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Calculated M.W.66kDa
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Observed M.W.67 kDa
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