-
Alternative name
IBP antibody
-
Catalog
A002325
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IHC
-
PurificationImmunogen affinity purified
-
Immunogendifferentially expressed in FDCP 6 homolog ( Mouse )
-
IHCImmunohistochemistry of paraffin-embedded human tonsillitis tissue slide using A002325( DEF6 Antibody) at dilution of 1:50
-
Western BlotJurkat cells were subjected to SDS PAGE followed by western blot with A002325( DEF6 Antibody) at dilution of 1:600
-
Recommended dilutionWB : 1:200-1:2000
-
Product Description specificalPhosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42. Can regulate cell morphology in cooperation with activated RAC1. Plays a role in Th2 (T helper cells) development and/or activation, perhaps by interfering with ZAP70 signaling (By similarity).
-
Gene nameDEF6
-
Uniprot IDQ9H4E7
-
Observed M.W.74 kDa
-