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Alternative name
AICDA, AID, ARP2, CDA2, Cytidine aminohydrolase, HIGM2 antibody
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Catalog
A000233
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB
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PurificationImmunogen affinity purified
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Immunogenactivation-induced cytidine deaminase
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Western BlotJurkat cells were subjected to SDS PAGE followed by western blot with A000233(AID antibody) at dilution of 1:800
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Recommended dilutionWB :1:200-1:2000
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Product Description specificalSingle-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class- switch recombination in B-lymphocytes. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.
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locationCytoplasm,Nucleus
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Uniprot IDQ9GZX7
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Calculated M.W.24kDa,observed 50kDa
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