Product Categories
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Alternative name
DR1, NC2 BETA, NC2, Negative cofactor 2 beta, Protein Dr1 antibody
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Catalog
A002527
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogendown-regulator of transcription 1, TBP-binding (negative cofactor 2)
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IHCImmunohistochemistry of paraffin-embedded human breast cancer using A002527(DR1 antibody) at dilution of 1:10
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Western Blotmouse testis tissue were subjected to SDS PAGE followed by western blot with A002527(DR1 antibody) at dilution of 1:1000
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalThe association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
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Gene nameDR1
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Uniprot IDQ01658
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Observed M.W.19-20kd
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