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Alternative name
RBBP3 antibody
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Catalog
A002600
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,IHC,WB
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PurificationImmunogen affinity purified
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ImmunogenE2F transcription factor 1
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IHCImmunohistochemistry of paraffin-embedded human breast cancer using A002600(E2F1 antibody) at dilution of 1:50
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Western Blotmouse brain tissue were subjected to SDS PAGE followed by western blot with A002600( E2F1 Antibody) at dilution of 1:300
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Recommended dilutionWB : 1:200-1:1000
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Product Description specificalTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters (PubMed:20176812).
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Gene nameE2F1
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Uniprot IDQ01094
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Observed M.W.55 kDa
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