-
Alternative name
EGFR, ERBB, ERBB1, HER1, mENA, PIG61, Proto oncogene c ErbB 1 antibody
-
Catalog
A002667
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman
-
Applications Tested/SuitableELISA,WB,IHC,FC
-
PurificationImmunogen affinity purified
-
Immunogenepidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
-
IHCImmunohistochemistry of paraffin-embedded human lung cancer slide using A002667( EGFR Antibody) at dilution of 1:50
-
Western BlotA431 cells were subjected to SDS PAGE followed by western blot with A002667( EGFR Antibody) at dilution of 1:2000
-
Recommended dilutionWB:1:1000-1:10000;IHC:1:50-1:500
-
Product Description specificalERBB1, also mamed as EGFR, is a receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. ERBB1 is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with C-SRC and CTNNB1/beta-catenin. Isoform 2/truncated isoform of ERBB1 may act as an antagonist. EGFR is associated with lung cancer. The antibody can recognize all the isoforms.
-
Uniprot IDP00533
-
Calculated M.W.140kDa
-