-
Alternative name
COFS4, ERCC1, UV20 antibody
-
Catalog
A002832
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IHC,IP
-
PurificationImmunogen affinity purified
-
Immunogenexcision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
-
IHCImmunohistochemistry of paraffin-embedded human testis using A002832(ERCC1 antibody) at dilution of 1:50
-
Western BlotMCF7 cells were subjected to SDS PAGE followed by western blot with A002832(ERCC1 antibody) at dilution of 1:300
-
Recommended dilutionWB : 1:500-1:5000
-
Product Description specificalIsoform 1: Non-catalytic component of a structure- specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.
-
Gene nameERCC1
-
Uniprot IDP07992
-
Observed M.W.36-38 kDa
-