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Alternative name
ERK, ERK 1, ERK1, ERK1/2, ERT2, HS44KDAP, HUMKER1A, Insulin stimulated MAP2 kinase, MAP kinase 3, MAP kinase isoform p44,MAPK 3, MAPK3, p44 ERK1, p44 MAPK, P44ERK1, P44MAPK, PRKM3 antibody
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Catalog
A002844
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB,IHC,IF
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PurificationImmunogen affinity purified
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Immunogenmitogen-activated protein kinase 3
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IHCImmunohistochemistry of paraffin-embedded human breast cancer using A002844( ERK1/2 antibody) at dilution of 1:50
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Western BlotA375 cells were subjected to SDS PAGE followed by western blot with A002844( ERK1/2 antibody) at dilution of 1:1000
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Recommended dilutionIHC:1:20-1:200;IF:1:10-1:100
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Product Description specificalERK1 and ERK2 belongs to the protein kinase superfamily. It is involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. ERK1/2 catalized the reaction: ATP + a protein = ADP + a phosphoprotein. It is activated by tyrosine phosphorylation in response to insulin and NGF. This antibody can recognize both ERK1 and ERK2.
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Gene nameMAPK3
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locationCytoplasm,ucleus
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Uniprot IDP27361
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Calculated M.W.44kDa
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Observed M.W.38-44 kDa
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