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Alternative name
C14orf114 , antibody
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Catalog
A002890
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IF,IHC,IP
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PurificationImmunogen affinity purified
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Immunogenexonuclease 3'-5' domain containing 2
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IHCImmunohistochemistry of paraffin-embedded human testis using A002890(EXD2 antibody) at dilution of 1:50
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Western Blotmouse lung tissue were subjected to SDS PAGE followed by western blot with A002890(EXD2 antibody) at dilution of 1:300
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalExonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.
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Gene nameEXD2
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Uniprot IDQ9NVH0
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Observed M.W.56 kDa
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