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Alternative name
ADTAA, alpha Adaptin, Alpha adaptin A, Alpha1 adaptin, AP 2 complex subunit alpha 1, AP2 ALPHA, AP2A1, CLAPA1 antibody
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Catalog
A000323
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IP,IF
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PurificationImmunogen affinity purified
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Immunogenadaptor-related protein complex 2, alpha 1 subunit
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IHCImmunohistochemistry of paraffin-embedded human ovary tumor using A000323(AP2A1 antibody) at dilution of 1:50
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Western BlotHEK-293 cells were subjected to SDS PAGE followed by western blot with A000323(AP2A1 antibody) at dilution of 1:1000
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Recommended dilutionWB :1:500-1:5000;IP:1:500-1:5000;IHC:1:20-1:200;IF:1:10-1:100
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Product Description specificalAP2A1 encodes adaptor protein complex 2 (AP-2) subunit alpha-1, which is a 100 kDa coated vesicle protein. Adaptor protein (AP) complexes are cytosolic heterotetramers that mediate the sorting of membrane proteins in the secretory and endocytic pathways. AP complexes are involved in the formation of clathrin-coated vesicles (CCVs) by recruiting the scaffold protein, clathrin. AP complexes also play a pivotal role in the cargo selection by recognizing the sorting signals within the cytoplasmic tail of integral membrane proteins. AP-2 is involved in clathrin-dependent endocytosis.
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Gene nameAP2A1
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locationCell membrane,Coated pit,Membrane
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Uniprot IDO95782
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Calculated M.W.108kDa
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Observed M.W.108 kDa
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