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Alternative name
KIAA0571 antibody
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Catalog
A003272
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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ImmunogenGRB2-associated binding protein 2
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IHCImmunohistochemistry of paraffin-embedded human breast cancer tissue slide using A003272( GAB2 Antibody) at dilution of 1:50
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Western BlotMCF-7 cells were subjected to SDS PAGE followed by western blot with A003272( GAB2 Antibody) at dilution of 1:600
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalAdapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
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Gene nameGAB2
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Uniprot IDQ9UQC2
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Observed M.W.70-74 kDa
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