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Alternative name
Ganglioside GM2 activator, GM2 AP, GM2 ganglioside activator, GM2A, SAP 3 antibody
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Catalog
A003517
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse ,Rat
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Applications Tested/SuitableELISA,IHC,WB,IP
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PurificationImmunogen affinity purified
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ImmunogenGM2 ganglioside activator
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IHCImmunohistochemistry of paraffin-embedded human colon cancer using A003517(GM2A antibody) at dilution of 1:100
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Western Blotrat kidney tissue were subjected to SDS PAGE followed by western blot with A003517( GM2A Antibody) at dilution of 1:300
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Recommended dilutionWB : 1:200-1:1000
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Product Description specificalThe large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity (By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta- hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.
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Gene nameGM2A
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Uniprot IDP17900
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Observed M.W.22 kDa
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