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Alternative name
M6A antibody
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Catalog
A003584
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IP,IHC
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PurificationImmunogen affinity purified
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Immunogenglycoprotein M6A
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IHCImmunohistochemistry of paraffin-embedded human brain using A003584(GPM6A antibody) at dilution of 1:50
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Western Blotmouse retina tissue were subjected to SDS PAGE followed by western blot with A003584(GPM6A antibody) at dilution of 1:600
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalInvolved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G- protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
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Gene nameGPM6A
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Uniprot IDP51674
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Observed M.W.31 kDa
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