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Alternative name
CGL1, CSPB, CTLA1, GRB antibody
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Catalog
A003737
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman
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Applications Tested/SuitableELISA,WB,IHC,IF
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PurificationImmunogen affinity purified
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Immunogengranzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
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IHCImmunohistochemistry of paraffin-embedded human lymphoma using A003737(GZMB antibody) at dilution of 1:100
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Western BlotHL-60 cells were subjected to SDS PAGE followed by western blot with A003737(GZMB antibody) at dilution of 1:500
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalThis enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
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Gene nameGZMB
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Uniprot IDP10144
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Observed M.W.33 kDa
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