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Alternative name
AMPK gamma1, AMPK subunit gamma 1, AMPKG, PRKAG1 antibody
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Catalog
A000379
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogenprotein kinase, AMP-activated, gamma 1 non-catalytic subunit
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IHCImmunohistochemistry of paraffin-embedded human testis tissue slide using A000379( PRKAG1 Antibody) at dilution of 1:50
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Western BlotK-562 cells were subjected to SDS PAGE followed by western blot with A000379( PRKAG1 Antibody) at dilution of 1:1000
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Recommended dilutionWB :1:500-1:5000;IHC:1:20-1:200
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Product Description specificalProtein kinase, AMP-activated, gamma 1 non-catalytic subunit (PRKAG1, synonyms: AMPKG, MGC8666) is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an catalytic subunit, and non-catalytic and subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and -hydroxy-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK.
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Gene namePRKAG1
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locationcytosol,ucleoplasm,embrane
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Uniprot IDP54619
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Calculated M.W.38kDa
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Observed M.W.35-38 kDa
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