-
Alternative name
KIAA0288 antibody
-
Catalog
A003800
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IHC,IP
-
PurificationImmunogen affinity purified
-
Immunogenhistone deacetylase 4
-
IHCImmunohistochemistry of paraffin-embedded human kidney using A003800(HDAC4 antibody) at dilution of 1:100
-
Western BlotHeLa cells were subjected to SDS PAGE followed by western blot with A003800(HDAC4 antibody) at dilution of 1:300
-
Recommended dilutionWB : 1:200-1:2000
-
Product Description specificalResponsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
-
Gene nameHDAC4
-
Uniprot IDP56524
-
Observed M.W.119-140kd
-