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Alternative name
Amylin, DAP, Diabetes associated peptide, IAP, IAPP, Insulinoma amyloid peptide, islet amyloid polypeptide antibody
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Catalog
A000384
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman
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Applications Tested/SuitableELISA,IHC
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PurificationImmunogen affinity purified
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Immunogenislet amyloid polypeptide
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IHCImmunohistochemistry of paraffin-embedded human pancreas tissue slide using A000384( Amylin Antibody) at dilution of 1:50
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Recommended dilutionIHC:1:20-1:200
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Product Description specificalIAPP, also known as Amylin, is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. IAPP is co-secreted with insulin by pancreatic β-cells and largely contributes to glycemic control. Studies suggest that this protein, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
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Gene nameIAPP
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locationAmyloid,Secreted
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Uniprot IDP10997
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Calculated M.W.10kDa
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