-
Alternative name
HOD, HOP, LAGY, NECC1, OB1 antibody
-
Catalog
A003970
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,IP,WB
-
PurificationImmunogen affinity purified
-
ImmunogenHOP homeobox
-
Recommended dilutionWB : 1:200-1:2000
-
Product Description specificalAtypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor.
-
Gene nameHOPX
-
Uniprot IDQ9BPY8
-
Observed M.W.8-12kd
-