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Alternative name
FLJ95963, FLJ96005, IL 17 receptor C, IL 17RC, IL 17RL, IL17 RL, IL17RC, IL17Rhom, IL17RL, interleukin 17 receptor C, ZcytoR14 antibody
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Catalog
A004231
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB
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PurificationImmunogen affinity purified
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Immunogeninterleukin 17 receptor C
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Recommended dilutionWB : 1:200-1:1000
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Product Description specificalReceptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA (PubMed:16785495). Receptor for the heterodimer formed by IL17A and IL17B as part of a heterodimeric complex with IL17RA (PubMed:18684971). Has also been shown to be the cognate receptor for IL17F and to bind IL17A with high affinity without the need for IL17RA (PubMed:17911633). Activation of IL17RC leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1 (PubMed:16785495). _x000D_Isoform 5: Receptor for both IL17A and IL17F. _x000D_Isoform 6: Does not bind IL17A or IL17F. _x000D_Isoform 7: Does not bind IL17A or IL17F. _x000D_Isoform 8: Receptor for both IL17A and IL17F.
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Gene nameIL17RC
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Uniprot IDQ8NAC3
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Observed M.W.45-50kd
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