-
Alternative name
DKFZp686F0244, interferon regulatory factor 2, IRF 2, IRF2 antibody
-
Catalog
A004386
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IHC,IP
-
PurificationImmunogen affinity purified
-
Immunogeninterferon regulatory factor 2
-
IHCImmunohistochemistry of paraffin-embedded human colon cancer using A004386(IRF2 antibody) at dilution of 1:50
-
Western BlotJurkat cells were subjected to SDS PAGE followed by western blot with A004386(IRF2 antibody) at dilution of 1:500
-
Recommended dilutionWB : 1:200-1:2000
-
Product Description specificalSpecifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.
-
Gene nameIRF2
-
Uniprot IDP14316
-
Observed M.W.50 kDa
-