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Alternative name
MUM1 antibody
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Catalog
A004390
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,IHC,WB,IP
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PurificationImmunogen affinity purified
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Immunogeninterferon regulatory factor 4
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IHCImmunohistochemistry of paraffin-embedded human lymphoma using A004390(IRF4 antibody) at dilution of 1:50
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Western Blotmouse spleen tissue were subjected to SDS PAGE followed by western blot with A004390( IRF4 Antibody) at dilution of 1:1000
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Product Description specificalTranscriptional activator. Binds to the interferon- stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes (By similarity).
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Uniprot IDQ15306
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