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Alternative name
ANO2, anoctamin 2, C12orf3, DKFZp434P102, TMEM16B, Transmembrane protein 16B antibody
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Catalog
A000442
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IF,IP,IHC
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PurificationImmunogen affinity purified
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Immunogenanoctamin 2
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IHCImmunohistochemistry of paraffin-embedded human breast cancer tissue slide using A000442( ANO2 Antibody) at dilution of 1:50
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Western Blotmouse brain tissue were subjected to SDS PAGE followed by western blot with A000442(ANO2 antibody) at dilution of 1:500
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Recommended dilutionWB :1:1000-1:10000;IHC:1:20-1:200;IF:1:10-1:100;IP:1:200-1:1000
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Product Description specificalCalcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina.
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Gene nameANO2
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locationCell membrane?
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Uniprot IDQ9NQ90
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Calculated M.W.114kDa
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Observed M.W.114kd
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