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Alternative name
ARA3, FLARA3, KIAA0850, NS1, NS1BP antibody
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Catalog
A004428
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogeninfluenza virus NS1A binding protein
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IHCImmunohistochemistry of paraffin-embedded human kidney using A004428(IVNS1ABP antibody) at dilution of 1:100
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Western Blotmouse heart tissue were subjected to SDS PAGE followed by western blot with A004428(IVNS1ABP antibody) at dilution of 1:800
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalPlays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines (By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.
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Gene nameIVNS1ABP
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Uniprot IDQ9Y6Y0
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Observed M.W.70 kDa
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