anti-KARS antibody

Alternative name
KIAA0070 antibody
Catalog
A004467
Size100μg
Formliquid
Purity≥95% as determined by SDS-PAGE
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
ClonalityPolyclonal Antibody
Host Rabbit
Species ReactivityHuman, Mouse ,Rat
Applications Tested/SuitableELISA,WB,IHC
PurificationImmunogen affinity purified
Immunogenlysyl-tRNA synthetase
IHCImmunohistochemistry of paraffin-embedded human placenta using A004467(KARS antibody) at dilution of 1:100
Western BlotHeLa cells were subjected to SDS PAGE followed by western blot with A004467(KARS antibody) at dilution of 1:400
Recommended dilutionWB : 1:500-1:5000
Product Description specificalCatalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of diadenosine oligophosphate (Ap4A), a signaling molecule involved in the activation of MITF transcriptional activity. Interacts with HIV-1 virus GAG protein, facilitating the selective packaging of tRNA(3)(Lys), the primer for reverse transcription initiation.
Gene nameKARS
Uniprot IDQ15046
Observed M.W.68 kDa

KIAA0070 antibody