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Alternative name
KIAA0413 antibody
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Catalog
A000470
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Rat
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Applications Tested/SuitableELISA,WB,IHC,IP,IF
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PurificationImmunogen affinity purified
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Immunogenapoptotic peptidase activating factor 1
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IHCImmunohistochemistry of paraffin-embedded human heart tissue slide using A000470( APAF1 Antibody) at dilution of 1:200
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Western BlotHEK-293 cells were subjected to SDS PAGE followed by western blot with A000470(APAF1 antibody) at dilution of 1:500
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalOligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
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Gene nameAPAF1
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Uniprot IDO14727
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Observed M.W.130-142 kDa
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