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Alternative name
MBD3 antibody
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Catalog
A005035
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IF,IP
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PurificationImmunogen affinity purified
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Immunogenmethyl-CpG binding domain protein 3
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IHCImmunohistochemistry of paraffin-embedded human endometrial cancer using A005035(MBD3 antibody) at dilution of 1:100
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Western BlotY79 cells were subjected to SDS PAGE followed by western blot with A005035(MBD3 antibody) at dilution of 1:600
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalActs as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (PubMed:12124384). Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (PubMed:24307175). Recruits histone deacetylases and DNA methyltransferases.
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Gene nameMBD3
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Uniprot IDO95983
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Observed M.W.33 kDa
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